Center for Biophysics & Computational Biology


At the intersection of biology, chemistry, and biophysics, CB2 researchers perform computational, theoretical and experimental research on defining problems in structural biology, molecular recognition and the evolution of proteins.

Current Projects

Activities include development of new multi-scale models, effective potentials, and sampling methods for molecular simulations; protein folding and misfolding; fundamental physics and health-related applications; ligand binding to protein receptors and drug design; and protein evolution, stability, and drug resistance.


Ronald M. Levy
CB2, Director
Laura H. Carnell Professor of Biophysics and Computational Biology

Center for Biophysics & Computational Biology (CB2)

Science Education and Research Center, 7th floor
1925 North 12th Street
Philadelphia, PA 19122