Center for Biophysics & Computational Biology
The Center for Biophysics & Computational Biology (CB2) is home to leading-edge computational research at the intersection of biology, chemistry, and biophysics. Researchers at CB2 perform theoretical and experimental research on defining problems in structural biology, molecular recognition, and the evolution of proteins. Molecular simulations have come to play a central role in these fields as they help us to develop our intuition about the behavior of models which link biological structures to function. Protein folding and misfolding, ligand binding and molecular recognition, biological machines used for transport and signaling, these are some of the research areas greatly enriched by computational approaches based on molecular simulations.
Current research activities at CB2 include the development of new multi-scale models, effective potentials, and sampling methods for molecular simulations; protein folding and misfolding; fundamental physics and health related applications; ligand binding to protein receptors and drug design; protein evolution, stability, and drug resistance; and bioinformatics and biophysics.
Ronald M. Levy, Director
Laura H. Carnell Professor of Biophysics and Computational Biology